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Oral Delivery of the Sj23LHD-GST Antigen by Salmonella typhimurium Type III Secretion System Protects against Schistosoma japonicum Infection in Mice

BACKGROUND: Schistosomiasis japonica is a zoonotic parasitic disease and oral vaccine delivery system would be benefit for prevention of this disease. Although attenuated salmonella has been used as an antigen expression vector for oral vaccine development, the membrane-bound vacuoles in which bacte...

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Detalles Bibliográficos
Autores principales: Chen, Guo, Dai, Yang, Chen, Jianxiang, Wang, Xiaoting, Tang, Bo, Zhu, Yinchang, Hua, Zichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167783/
https://www.ncbi.nlm.nih.gov/pubmed/21909450
http://dx.doi.org/10.1371/journal.pntd.0001313