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Parallelized short read assembly of large genomes using de Bruijn graphs

BACKGROUND: Next-generation sequencing technologies have given rise to the explosive increase in DNA sequencing throughput, and have promoted the recent development of de novo short read assemblers. However, existing assemblers require high execution times and a large amount of compute resources to...

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Detalles Bibliográficos
Autores principales: Liu, Yongchao, Schmidt, Bertil, Maskell, Douglas L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167803/
https://www.ncbi.nlm.nih.gov/pubmed/21867511
http://dx.doi.org/10.1186/1471-2105-12-354