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Macrophage Replication Screen Identifies a Novel Francisella Hydroperoxide Resistance Protein Involved in Virulence

Francisella tularensis is a Gram-negative facultative intracellular pathogen and the causative agent of tularemia. Recently, genome-wide screens have identified Francisella genes required for virulence in mice. However, the mechanisms by which most of the corresponding proteins contribute to pathoge...

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Detalles Bibliográficos
Autores principales: Llewellyn, Anna C., Jones, Crystal L., Napier, Brooke A., Bina, James E., Weiss, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167825/
https://www.ncbi.nlm.nih.gov/pubmed/21915295
http://dx.doi.org/10.1371/journal.pone.0024201