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P2X7 Receptor and Caspase 1 Activation Are Central to Airway Inflammation Observed after Exposure to Tobacco Smoke

Chronic Obstructive Pulmonary Disease (COPD) is a cigarette smoke (CS)-driven inflammatory airway disease with an increasing global prevalence. Currently there is no effective medication to stop the relentless progression of this disease. It has recently been shown that an activator of the P2X7/infl...

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Detalles Bibliográficos
Autores principales: Eltom, Suffwan, Stevenson, Christopher S., Rastrick, Joseph, Dale, Nicole, Raemdonck, Kristof, Wong, Sissie, Catley, Matthew C., Belvisi, Maria G., Birrell, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167831/
https://www.ncbi.nlm.nih.gov/pubmed/21915284
http://dx.doi.org/10.1371/journal.pone.0024097