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Tension, Free Space, and Cell Damage in a Microfluidic Wound Healing Assay

We use a novel, microfluidics-based technique to deconstruct the classical wound healing scratch assay, decoupling the contribution of free space and cell damage on the migratory dynamics of an epithelial sheet. This method utilizes multiple laminar flows to selectively cleave cells enzymatically, a...

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Detalles Bibliográficos
Autores principales: Murrell, Michael, Kamm, Roger, Matsudaira, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167843/
https://www.ncbi.nlm.nih.gov/pubmed/21915305
http://dx.doi.org/10.1371/journal.pone.0024283