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Roles of Dynein and Dynactin in Early Endosome Dynamics Revealed Using Automated Tracking and Global Analysis

Microtubule-dependent movement is crucial for the spatial organization of endosomes in most eukaryotes, but as yet there has been no systematic analysis of how a particular microtubule motor contributes to early endosome dynamics. Here we tracked early endosomes labeled with GFP-Rab5 on the nanomete...

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Detalles Bibliográficos
Autores principales: Flores-Rodriguez, Neftali, Rogers, Salman S., Kenwright, David A., Waigh, Thomas A., Woodman, Philip G., Allan, Victoria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167862/
https://www.ncbi.nlm.nih.gov/pubmed/21915335
http://dx.doi.org/10.1371/journal.pone.0024479