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Pneumococcal DNA is not detectable in the blood of healthy carrier children by real-time PCR targeting the lytA gene
The diagnosis of invasive pneumococcal disease (IPD) is currently based on culture methods, which lack sensitivity, especially after antibiotic therapy. Molecular methods have improved sensitivity and do not require viable bacteria; however, their use is complicated by reports of low specificity wit...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for General Microbiology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167920/ https://www.ncbi.nlm.nih.gov/pubmed/21349984 http://dx.doi.org/10.1099/jmm.0.028357-0 |