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Mechanism of Actin Filament Nucleation by the Bacterial Effector VopL

Vibrio parahaemolyticus protein L (VopL) is an actin nucleation factor that induces stress fibers when injected by bacteria into eukaryotic host cells. VopL contains three N-terminal Wiskott-Aldrich Homology 2 (WH2) motifs and a unique VopL C-terminal domain (VCD). We describe crystallographic and b...

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Detalles Bibliográficos
Autores principales: Yu, Bingke, Cheng, Hui-Chun, Brautigam, Chad A., Tomchick, Diana R., Rosen, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168117/
https://www.ncbi.nlm.nih.gov/pubmed/21873984
http://dx.doi.org/10.1038/nsmb.2110