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Differential gene expression between wild-type and Gulo-deficient mice supplied with vitamin C

The aim of this study was to test the hypothesis that hepatic vitamin C (VC) levels in VC deficient mice rescued with high doses of VC supplements still do not reach the optimal levels present in wild-type mice. For this, we used a mouse scurvy model (sfx) in which the L-gulonolactone oxidase gene (...

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Detalles Bibliográficos
Autores principales: Jiao, Yan, Zhang, Jifei, Yan, Jian, Stuart, John, Gibson, Griffin, Lu, Lu, Willaims, Robert, Wang, Yong Jun, Gu, Weikuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168176/
https://www.ncbi.nlm.nih.gov/pubmed/21931508
http://dx.doi.org/10.1590/S1415-47572011005000031