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Determination of β(S) haplotypes in patients with sickle-cell anemia in the state of Rio Grande do Norte, Brazil
β(S) haplotypes were studied in 47 non-related patients with sickle-cell anemia from the state of Rio Grande do Norte, Brazil. Molecular analysis was conducted by PCR/RFLP using restriction endonucleases XmnI, HindIII, HincII and HinfI to analyze six polymorphic sites from the beta cluster. Twenty-s...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Genética
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168181/ https://www.ncbi.nlm.nih.gov/pubmed/21931513 http://dx.doi.org/10.1590/S1415-47572011005000027 |