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Use of a Designed Peptide Library to Screen for Binders to a Particular DNA G-Quadruplex Sequence
We demonstrated a method to screen for binders to a particular G-quadruplex sequence using easily designed short peptides consisting of naturally occurring amino acids and mining of binding data using statistical methods such as hierarchical clustering analysis (HCA). Despite the small size of the l...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168274/ https://www.ncbi.nlm.nih.gov/pubmed/21912736 http://dx.doi.org/10.4061/2011/572873 |