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Cellular toxicity of expanded RNA repeats: focus on RNA foci

Discrete and punctate nuclear RNA foci are characteristic molecular hallmarks of pathogenesis in myotonic dystrophy type 1 and type 2. Intranuclear RNA inclusions of distinct morphology have also been found in fragile X-associated tremor ataxia syndrome, Huntington's disease-like 2, spinocerebe...

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Detalles Bibliográficos
Autores principales: Wojciechowska, Marzena, Krzyzosiak, Wlodzimierz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168290/
https://www.ncbi.nlm.nih.gov/pubmed/21729883
http://dx.doi.org/10.1093/hmg/ddr299