Bioluminescent Imaging Reveals Divergent Viral Pathogenesis in Two Strains of Stat1-Deficient Mice, and in αßγ Interferon Receptor-Deficient Mice

Pivotal components of the IFN response to virus infection include the IFN receptors (IFNR), and the downstream factor signal transducer and activator of transcription 1 (Stat1). Mice deficient for Stat1 and IFNR (Stat1(−/−) and IFNαßγR(−/−) mice) lack responsiveness to IFN and exhibit high sensitivi...

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Detalles Bibliográficos
Autores principales: Pasieka, Tracy Jo, Collins, Lynne, O'Connor, Megan A., Chen, Yufei, Parker, Zachary M., Berwin, Brent L., Piwnica-Worms, David R., Leib, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168466/
https://www.ncbi.nlm.nih.gov/pubmed/21915277
http://dx.doi.org/10.1371/journal.pone.0024018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168466/
https://www.ncbi.nlm.nih.gov/pubmed/21915277
http://dx.doi.org/10.1371/journal.pone.0024018

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