Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

Cerebrovascular lesions related to congophilic amyloid angiopathy (CAA) often accompany deposition of β-amyloid (Aβ) in Alzheimer’s disease (AD), leading to disturbed cerebral blood flow and cognitive dysfunction, posing the question how cerebrovascular pathology contributes to the pathology of AD....

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Detalles Bibliográficos
Autores principales: Merlini, Mario, Meyer, Eric P., Ulmann-Schuler, Alexandra, Nitsch, Roger M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168476/
https://www.ncbi.nlm.nih.gov/pubmed/21688176
http://dx.doi.org/10.1007/s00401-011-0834-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168476/
https://www.ncbi.nlm.nih.gov/pubmed/21688176
http://dx.doi.org/10.1007/s00401-011-0834-y

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