Genetic Background Strongly Modifies the Severity of Symptoms of Hirschsprung Disease, but Not Hearing Loss in Rats Carrying Ednrb(sl) Mutations

Hirschsprung disease (HSCR) is thought to result as a consequence of multiple gene interactions that modulate the ability of enteric neural crest cells to populate the developing gut. However, it remains unknown whether the single complete deletion of important HSCR-associated genes is sufficient to...

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Detalles Bibliográficos
Autores principales: Dang, Ruihua, Torigoe, Daisuke, Suzuki, Sari, Kikkawa, Yoshiaki, Moritoh, Kanako, Sasaki, Nobuya, Agui, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168492/
https://www.ncbi.nlm.nih.gov/pubmed/21915282
http://dx.doi.org/10.1371/journal.pone.0024086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168492/
https://www.ncbi.nlm.nih.gov/pubmed/21915282
http://dx.doi.org/10.1371/journal.pone.0024086

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