LEDGF(1-326) Decreases P23H and Wild Type Rhodopsin Aggregates and P23H Rhodopsin Mediated Cell Damage in Human Retinal Pigment Epithelial Cells

BACKGROUND: P23H rhodopsin, a mutant rhodopsin, is known to aggregate and cause retinal degeneration. However, its effects on retinal pigment epithelial (RPE) cells are unknown. The purpose of this study was to determine the effect of P23H rhodopsin in RPE cells and further assess whether LEDGF(1-32...

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Detalles Bibliográficos
Autores principales: Baid, Rinku, Scheinman, Robert I., Shinohara, Toshimichi, Singh, Dhirendra P., Kompella, Uday B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168525/
https://www.ncbi.nlm.nih.gov/pubmed/21915354
http://dx.doi.org/10.1371/journal.pone.0024616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168525/
https://www.ncbi.nlm.nih.gov/pubmed/21915354
http://dx.doi.org/10.1371/journal.pone.0024616

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