Aberrant Hepatic Methionine Metabolism and Gene Methylation in the Pathogenesis and Treatment of Alcoholic Steatohepatitis

The pathogenesis of alcoholic steatohepatitis (ASH) involves ethanol-induced aberrations in hepatic methionine metabolism that decrease levels of S-adenosylmethionine (SAM), a compound which regulates the synthesis of the antioxidant glutathione and is the principal methyl donor in the epigenetic re...

Descripción completa

Detalles Bibliográficos
Autores principales: Halsted, Charles H., Medici, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168767/
https://www.ncbi.nlm.nih.gov/pubmed/22007317
http://dx.doi.org/10.1155/2012/959746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168767/
https://www.ncbi.nlm.nih.gov/pubmed/22007317
http://dx.doi.org/10.1155/2012/959746

Ejemplares similares