Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination

4-Fluoropyrazole systems may be prepared by a single, sequential telescoped two-step continuous gas/liquid–liquid/liquid flow process from diketone, fluorine gas and hydrazine starting materials.

Detalles Bibliográficos
Autores principales: Breen, Jessica R, Sandford, Graham, Yufit, Dmitrii S, Howard, Judith A K, Fray, Jonathan, Patel, Bhairavi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168861/
https://www.ncbi.nlm.nih.gov/pubmed/21915207
http://dx.doi.org/10.3762/bjoc.7.120
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author Breen, Jessica R
Sandford, Graham
Yufit, Dmitrii S
Howard, Judith A K
Fray, Jonathan
Patel, Bhairavi
author_facet Breen, Jessica R
Sandford, Graham
Yufit, Dmitrii S
Howard, Judith A K
Fray, Jonathan
Patel, Bhairavi
author_sort Breen, Jessica R
collection PubMed
description 4-Fluoropyrazole systems may be prepared by a single, sequential telescoped two-step continuous gas/liquid–liquid/liquid flow process from diketone, fluorine gas and hydrazine starting materials.
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spelling pubmed-31688612011-09-13 Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination Breen, Jessica R Sandford, Graham Yufit, Dmitrii S Howard, Judith A K Fray, Jonathan Patel, Bhairavi Beilstein J Org Chem Full Research Paper 4-Fluoropyrazole systems may be prepared by a single, sequential telescoped two-step continuous gas/liquid–liquid/liquid flow process from diketone, fluorine gas and hydrazine starting materials. Beilstein-Institut 2011-08-02 /pmc/articles/PMC3168861/ /pubmed/21915207 http://dx.doi.org/10.3762/bjoc.7.120 Text en Copyright © 2011, Breen et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Breen, Jessica R
Sandford, Graham
Yufit, Dmitrii S
Howard, Judith A K
Fray, Jonathan
Patel, Bhairavi
Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination
title Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination
title_full Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination
title_fullStr Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination
title_full_unstemmed Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination
title_short Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination
title_sort continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168861/
https://www.ncbi.nlm.nih.gov/pubmed/21915207
http://dx.doi.org/10.3762/bjoc.7.120
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