Allopregnanolone Promotes Regeneration and Reduces β-Amyloid Burden in a Preclinical Model of Alzheimer's Disease

Previously, we demonstrated that allopregnanolone (APα) promoted proliferation of rodent and human neural progenitor cells in vitro. Further, we demonstrated that APα promoted neurogenesis in the hippocampal subgranular zone (SGZ) and reversed learning and memory deficits in the male triple transgen...

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Detalles Bibliográficos
Autores principales: Chen, Shuhua, Wang, Jun Ming, Irwin, Ronald W., Yao, Jia, Liu, Lifei, Brinton, Roberta Diaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168882/
https://www.ncbi.nlm.nih.gov/pubmed/21918687
http://dx.doi.org/10.1371/journal.pone.0024293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168882/
https://www.ncbi.nlm.nih.gov/pubmed/21918687
http://dx.doi.org/10.1371/journal.pone.0024293

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