Cargando…
Insight into G-DNA Structural Polymorphism and Folding from Sequence and Loop Connectivity through Free Energy Analysis
[Image: see text] The lengths of G-tracts and their connecting loop sequences determine G-quadruplex folding and stability. Complete understanding of the sequence–structure relationships remains elusive. Here, single-loop G-quadruplexes were investigated using explicit solvent molecular dynamics (MD...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2011
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168932/ https://www.ncbi.nlm.nih.gov/pubmed/21761922 http://dx.doi.org/10.1021/ja107805r |