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Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture
Alzheimer's disease (AD) is pathologically characterised by the age-dependent deposition of β-amyloid (Aβ) in senile plaques, intraneuronal accumulation of tau as neurofibrillary tangles, synaptic dysfunction and neuronal death. Neuroinflammation, typified by the accumulation of activated micro...
Autores principales: | Garwood, C J, Pooler, A M, Atherton, J, Hanger, D P, Noble, W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168992/ https://www.ncbi.nlm.nih.gov/pubmed/21633390 http://dx.doi.org/10.1038/cddis.2011.50 |
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