Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage

Acetaminophen (N-acetyl-para-aminophenol (APAP), paracetamol) is a commonly used analgesic and antipyretic agent. Although considered safe at therapeutic doses, accidental or intentional overdose causes acute liver failure characterized by centrilobular hepatic necrosis with high morbidity and morta...

Descripción completa

Detalles Bibliográficos
Autores principales: Badmann, A, Keough, A, Kaufmann, T, Bouillet, P, Brunner, T, Corazza, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168997/
https://www.ncbi.nlm.nih.gov/pubmed/21654829
http://dx.doi.org/10.1038/cddis.2011.55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168997/
https://www.ncbi.nlm.nih.gov/pubmed/21654829
http://dx.doi.org/10.1038/cddis.2011.55

Ejemplares similares