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Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage

Acetaminophen (N-acetyl-para-aminophenol (APAP), paracetamol) is a commonly used analgesic and antipyretic agent. Although considered safe at therapeutic doses, accidental or intentional overdose causes acute liver failure characterized by centrilobular hepatic necrosis with high morbidity and morta...

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Detalles Bibliográficos
Autores principales:	Badmann, A, Keough, A, Kaufmann, T, Bouillet, P, Brunner, T, Corazza, N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168997/ https://www.ncbi.nlm.nih.gov/pubmed/21654829 http://dx.doi.org/10.1038/cddis.2011.55

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