Insights from the molecular docking of withanolide derivatives to the target protein PknG from Mycobacterium tuberculosis

A crucial virulence factor for intracellular Mycobacterium tuberculosis survival is Protein kinase G (PknG), a eukaryotic-like serinethreonine protein kinase expressed by pathogenic mycobacteria that blocks the intracellular degradation of mycobacteria in lysosomes. Inhibition of PknG results in myc...

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Detalles Bibliográficos
Autores principales: Santhi, Natchimuthu, Aishwarya, Sekar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2011
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169209/
https://www.ncbi.nlm.nih.gov/pubmed/21904430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169209/
https://www.ncbi.nlm.nih.gov/pubmed/21904430

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