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Amine-linked diglycosides: Synthesis facilitated by the enhanced reactivity of allylic electrophiles, and glycosidase inhibition assays

Diglycose derivatives, consisting of two monosaccharides linked at non-anomeric positions by a bridging nitrogen atom, have been synthesised. Conversion of one of the precursor monosaccharide coupling components into an unsaturated derivative enhances its electrophilicity at the allylic position, fa...

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Detalles Bibliográficos
Autores principales: Cumpstey, Ian, Frigell, Jens, Pershagen, Elias, Akhtar, Tashfeen, Moreno-Clavijo, Elena, Robina, Inmaculada, Alonzi, Dominic S, Butters, Terry D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169339/
https://www.ncbi.nlm.nih.gov/pubmed/21915215
http://dx.doi.org/10.3762/bjoc.7.128