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Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis

Babesiosis is a tick-borne disease caused by eukaryotic Babesia parasites which are morphologically similar to Plasmodium falciparum, the causative agent of malaria in humans. Like Plasmodium, different species of Babesia are tuned to infect different mammalian hosts, including rats, dogs, horses an...

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Detalles Bibliográficos
Autores principales: Begley, Darren W., Edwards, Thomas E., Raymond, Amy C., Smith, Eric R., Hartley, Robert C., Abendroth, Jan, Sankaran, Banumathi, Lorimer, Donald D., Myler, Peter J., Staker, Bart L., Stewart, Lance J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169404/
https://www.ncbi.nlm.nih.gov/pubmed/21904052
http://dx.doi.org/10.1107/S1744309111029009