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Structure of thymidylate kinase from Ehrlichia chaffeensis
The enzyme thymidylate kinase phosphorylates the substrate thymidine 5′-phosphate (dTMP) to form thymidine 5′-diphosphate (dTDP), which is further phosphorylated to dTTP for incorporation into DNA. Ehrlichia chaffeensis is the etiologic agent of human monocytotropic erlichiosis (HME), a potentially...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169407/ https://www.ncbi.nlm.nih.gov/pubmed/21904055 http://dx.doi.org/10.1107/S174430911101493X |