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Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis

Owing to the evolution of multi-drug-resistant and extremely drug-resistant Mycobacterium tuberculosis strains, there is an urgent need to develop new antituberculosis strategies to prevent TB epidemics in the industrial world. Among the potential new drug targets are two small nonheme iron-binding...

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Detalles Bibliográficos
Autores principales: Buchko, Garry W., Hewitt, Stephen N., Napuli, Alberto J., Van Voorhis, Wesley C., Myler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169417/
https://www.ncbi.nlm.nih.gov/pubmed/21904065
http://dx.doi.org/10.1107/S1744309111008189