Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity

BACKGROUND: Both epidemiological and experimental studies suggest that heterozygosity for a single gene is linked with tumorigenesis and heterozygosity for two genes increases the risk of tumor incidence. Our previous work has demonstrated that Atm/Brca1 double heterozygosity leads to higher cell tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jufang, Su, Fengtao, Smilenov, Lubomir B, Zhou, Libin, Hu, Wentao, Ding, Nan, Zhou, Guangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169458/
https://www.ncbi.nlm.nih.gov/pubmed/21849032
http://dx.doi.org/10.1186/1748-717X-6-96

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169458/
https://www.ncbi.nlm.nih.gov/pubmed/21849032
http://dx.doi.org/10.1186/1748-717X-6-96

Ejemplares similares