Efficacy of Synaptic Inhibition Depends on Multiple, Dynamically Interacting Mechanisms Implicated in Chloride Homeostasis

Chloride homeostasis is a critical determinant of the strength and robustness of inhibition mediated by GABA(A) receptors (GABA(A)Rs). The impact of changes in steady state Cl(−) gradient is relatively straightforward to understand, but how dynamic interplay between Cl(−) influx, diffusion, extrusio...

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Detalles Bibliográficos
Autores principales: Doyon, Nicolas, Prescott, Steven A., Castonguay, Annie, Godin, Antoine G., Kröger, Helmut, De Koninck, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169517/
https://www.ncbi.nlm.nih.gov/pubmed/21931544
http://dx.doi.org/10.1371/journal.pcbi.1002149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169517/
https://www.ncbi.nlm.nih.gov/pubmed/21931544
http://dx.doi.org/10.1371/journal.pcbi.1002149

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