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Efficacy of Synaptic Inhibition Depends on Multiple, Dynamically Interacting Mechanisms Implicated in Chloride Homeostasis
Chloride homeostasis is a critical determinant of the strength and robustness of inhibition mediated by GABA(A) receptors (GABA(A)Rs). The impact of changes in steady state Cl(−) gradient is relatively straightforward to understand, but how dynamic interplay between Cl(−) influx, diffusion, extrusio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169517/ https://www.ncbi.nlm.nih.gov/pubmed/21931544 http://dx.doi.org/10.1371/journal.pcbi.1002149 |