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Transcriptome Kinetics Is Governed by a Genome-Wide Coupling of mRNA Production and Degradation: A Role for RNA Pol II

Transcriptome dynamics is governed by two opposing processes, mRNA production and degradation. Recent studies found that changes in these processes are frequently coordinated and that the relationship between them shapes transcriptome kinetics. Specifically, when transcription changes are counter-ac...

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Detalles Bibliográficos
Autores principales: Shalem, Ophir, Groisman, Bella, Choder, Mordechai, Dahan, Orna, Pilpel, Yitzhak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169527/
https://www.ncbi.nlm.nih.gov/pubmed/21931566
http://dx.doi.org/10.1371/journal.pgen.1002273