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Transcriptome Kinetics Is Governed by a Genome-Wide Coupling of mRNA Production and Degradation: A Role for RNA Pol II
Transcriptome dynamics is governed by two opposing processes, mRNA production and degradation. Recent studies found that changes in these processes are frequently coordinated and that the relationship between them shapes transcriptome kinetics. Specifically, when transcription changes are counter-ac...
Autores principales: | Shalem, Ophir, Groisman, Bella, Choder, Mordechai, Dahan, Orna, Pilpel, Yitzhak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169527/ https://www.ncbi.nlm.nih.gov/pubmed/21931566 http://dx.doi.org/10.1371/journal.pgen.1002273 |
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