Murine Gamma-herpesvirus Immortalization of Fetal Liver-Derived B Cells Requires both the Viral Cyclin D Homolog and Latency-Associated Nuclear Antigen

Human gammaherpesviruses are associated with the development of lymphoproliferative diseases and B cell lymphomas, particularly in immunosuppressed hosts. Understanding the molecular mechanisms by which human gammaherpesviruses cause disease is hampered by the lack of convenient small animal models...

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Detalles Bibliográficos
Autores principales: Liang, Xiaozhen, Paden, Clinton R., Morales, Francine M., Powers, Ryan P., Jacob, Joshy, Speck, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169539/
https://www.ncbi.nlm.nih.gov/pubmed/21931547
http://dx.doi.org/10.1371/journal.ppat.1002220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169539/
https://www.ncbi.nlm.nih.gov/pubmed/21931547
http://dx.doi.org/10.1371/journal.ppat.1002220

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