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Functional Dissection of the TBK1 Molecular Network

TANK-binding kinase 1 (TBK1) and inducible IκB-kinase (IKK-i) are central regulators of type-I interferon induction. They are associated with three adaptor proteins called TANK, Sintbad (or TBKBP1) and NAP1 (or TBKBP2, AZI2) whose functional relationship to TBK1 and IKK-i is poorly understood. We pe...

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Detalles Bibliográficos
Autores principales: Goncalves, Adriana, Bürckstümmer, Tilmann, Dixit, Evelyn, Scheicher, Ruth, Górna, Maria W., Karayel, Evren, Sugar, Cristina, Stukalov, Alexey, Berg, Tiina, Kralovics, Robert, Planyavsky, Melanie, Bennett, Keiryn L., Colinge, Jacques, Superti-Furga, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169550/
https://www.ncbi.nlm.nih.gov/pubmed/21931631
http://dx.doi.org/10.1371/journal.pone.0023971