Maturation-Induced Cloaking of Neutralization Epitopes on HIV-1 Particles

To become infectious, HIV-1 particles undergo a maturation process involving proteolytic cleavage of the Gag and Gag-Pol polyproteins. Immature particles contain a highly stable spherical Gag lattice and are impaired for fusion with target cells. The fusion impairment is relieved by truncation of th...

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Detalles Bibliográficos
Autores principales: Joyner, Amanda S., Willis, Jordan R., Crowe, James E., Aiken, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169560/
https://www.ncbi.nlm.nih.gov/pubmed/21931551
http://dx.doi.org/10.1371/journal.ppat.1002234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169560/
https://www.ncbi.nlm.nih.gov/pubmed/21931551
http://dx.doi.org/10.1371/journal.ppat.1002234

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