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Maturation-Induced Cloaking of Neutralization Epitopes on HIV-1 Particles
To become infectious, HIV-1 particles undergo a maturation process involving proteolytic cleavage of the Gag and Gag-Pol polyproteins. Immature particles contain a highly stable spherical Gag lattice and are impaired for fusion with target cells. The fusion impairment is relieved by truncation of th...
Autores principales: | Joyner, Amanda S., Willis, Jordan R., Crowe, James E., Aiken, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169560/ https://www.ncbi.nlm.nih.gov/pubmed/21931551 http://dx.doi.org/10.1371/journal.ppat.1002234 |
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