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Haplotype Estimation from Fuzzy Genotypes Using Penalized Likelihood

The Composite Link Model is a generalization of the generalized linear model in which expected values of observed counts are constructed as a sum of generalized linear components. When combined with penalized likelihood, it provides a powerful and elegant way to estimate haplotype probabilities from...

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Detalles Bibliográficos
Autores principales: Uh, Hae-Won, Eilers, Paul H. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169573/
https://www.ncbi.nlm.nih.gov/pubmed/21931662
http://dx.doi.org/10.1371/journal.pone.0024219