In Vivo RNAi Screen Reveals Neddylation Genes as Novel Regulators of Hedgehog Signaling

Hedgehog (Hh) signaling is highly conserved in all metazoan animals and plays critical roles in many developmental processes. Dysregulation of the Hh signaling cascade has been implicated in many diseases, including cancer. Although key components of the Hh pathway have been identified, significant...

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Detalles Bibliográficos
Autores principales: Du, Juan, Zhang, Junzheng, Su, Ying, Liu, Min, Ospina, Jason K., Yang, Shengyuan, Zhu, Alan Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169580/
https://www.ncbi.nlm.nih.gov/pubmed/21931660
http://dx.doi.org/10.1371/journal.pone.0024168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169580/
https://www.ncbi.nlm.nih.gov/pubmed/21931660
http://dx.doi.org/10.1371/journal.pone.0024168

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