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Bioluminescence-Based High-Throughput Screen Identifies Pharmacological Agents That Target Neurotransmitter Signaling in Small Cell Lung Carcinoma

BACKGROUND: Frontline treatment of small cell lung carcinoma (SCLC) relies heavily on chemotherapeutic agents and radiation therapy. Though SCLC patients respond well to initial cycles of chemotherapy, they eventually develop resistance. Identification of novel therapies against SCLC is therefore im...

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Detalles Bibliográficos
Autores principales: Improgo, Ma. Reina D., Johnson, Christopher W., Tapper, Andrew R., Gardner, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169587/
https://www.ncbi.nlm.nih.gov/pubmed/21931655
http://dx.doi.org/10.1371/journal.pone.0024132