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High Throughput Interrogation of Somatic Mutations in High Grade Serous Cancer of the Ovary

BACKGROUND: Epithelial ovarian cancer is the most lethal of all gynecologic malignancies, and high grade serous ovarian cancer (HGSC) is the most common subtype of ovarian cancer. The objective of this study was to determine the frequency and types of point somatic mutations in HGSC using a mutation...

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Detalles Bibliográficos
Autores principales: Matulonis, Ursula A., Hirsch, Michelle, Palescandolo, Emanuele, Kim, Eejung, Liu, Joyce, van Hummelen, Paul, MacConaill, Laura, Drapkin, Ronny, Hahn, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169600/
https://www.ncbi.nlm.nih.gov/pubmed/21931712
http://dx.doi.org/10.1371/journal.pone.0024433