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Structure of Apo- and Monometalated Forms of NDM-1—A Highly Potent Carbapenem-Hydrolyzing Metallo-β-Lactamase

The New Delhi Metallo-β-lactamase (NDM-1) gene makes multiple pathogenic microorganisms resistant to all known β-lactam antibiotics. The rapid emergence of NDM-1 has been linked to mobile plasmids that move between different strains resulting in world-wide dissemination. Biochemical studies revealed...

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Detalles Bibliográficos
Autores principales: Kim, Youngchang, Tesar, Christine, Mire, Joseph, Jedrzejczak, Robert, Binkowski, Andrew, Babnigg, Gyorgy, Sacchettini, James, Joachimiak, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169612/
https://www.ncbi.nlm.nih.gov/pubmed/21931780
http://dx.doi.org/10.1371/journal.pone.0024621