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The Human Endogenous Circadian System Causes Greatest Platelet Activation during the Biological Morning Independent of Behaviors

BACKGROUND: Platelets are involved in the thromboses that are central to myocardial infarctions and ischemic strokes. Such adverse cardiovascular events have day/night patterns with peaks in the morning (∼9AM), potentially related to endogenous circadian clock control of platelet activation. The obj...

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Detalles Bibliográficos
Autores principales: Scheer, Frank A. J. L., Michelson, Alan D., Frelinger, Andrew L., Evoniuk, Heather, Kelly, Erin E., McCarthy, Mary, Doamekpor, Lauren A., Barnard, Marc R., Shea, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169622/
https://www.ncbi.nlm.nih.gov/pubmed/21931750
http://dx.doi.org/10.1371/journal.pone.0024549