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Requirement of the CXXC Motif of Novel Francisella Infectivity Potentiator Protein B FipB, and FipA in Virulence of F. tularensis subsp. tularensis

The lipoprotein encoded by the Francisella tularensis subsp. tularensis locus FTT1103 is essential for virulence; an FTT1103 deletion mutant is defective in uptake and intracellular survival, and mice survive high dose challenges of greater than 10(8) bacteria. This protein has two conserved domains...

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Detalles Bibliográficos
Autores principales: Qin, Aiping, Scott, David W., Rabideau, Meaghan M., Moore, Emily A., Mann, Barbara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169626/
https://www.ncbi.nlm.nih.gov/pubmed/21931773
http://dx.doi.org/10.1371/journal.pone.0024611