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Discovery of IL-18 As a Novel Secreted Protein Contributing to Doxorubicin Resistance by Comparative Secretome Analysis of MCF-7 and MCF-7/Dox

BACKGROUND: Resistance to chemotherapy is the major cause of failure in breast cancer treatment. Recent studies suggest that secreted proteins may play important roles in chemoresistance. We sought to systematically characterize secreted proteins associated with drug resistance, which may represent...

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Detalles Bibliográficos
Autores principales: Yao, Ling, Zhang, Yan, Chen, Keying, Hu, Xiaofang, Xu, Lisa X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169632/
https://www.ncbi.nlm.nih.gov/pubmed/21931812
http://dx.doi.org/10.1371/journal.pone.0024684