A Selectable and Excisable Marker System for the Rapid Creation of Recombinant Poxviruses

BACKGROUND: Genetic manipulation of poxvirus genomes through attenuation, or insertion of therapeutic genes has led to a number of vector candidates for the treatment of a variety of human diseases. The development of recombinant poxviruses often involves the genomic insertion of a selectable marker...

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Detalles Bibliográficos
Autores principales: Rintoul, Julia L., Wang, Jiahu, Gammon, Don B., van Buuren, Nicholas J., Garson, Kenneth, Jardine, Karen, Barry, Michele, Evans, David H., Bell, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169633/
https://www.ncbi.nlm.nih.gov/pubmed/21931792
http://dx.doi.org/10.1371/journal.pone.0024643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169633/
https://www.ncbi.nlm.nih.gov/pubmed/21931792
http://dx.doi.org/10.1371/journal.pone.0024643

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