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A Selectable and Excisable Marker System for the Rapid Creation of Recombinant Poxviruses
BACKGROUND: Genetic manipulation of poxvirus genomes through attenuation, or insertion of therapeutic genes has led to a number of vector candidates for the treatment of a variety of human diseases. The development of recombinant poxviruses often involves the genomic insertion of a selectable marker...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169633/ https://www.ncbi.nlm.nih.gov/pubmed/21931792 http://dx.doi.org/10.1371/journal.pone.0024643 |