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In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation
Coagulase-positive Staphylococcus aureus (S. aureus) is the major causal pathogen of acute endocarditis, a rapidly progressing, destructive infection of the heart valves. Bacterial colonization occurs at sites of endothelial damage, where (together with fibrin and platelets) it initiates the formati...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169740/ https://www.ncbi.nlm.nih.gov/pubmed/21857652 http://dx.doi.org/10.1038/nm.2423 |