In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation

Coagulase-positive Staphylococcus aureus (S. aureus) is the major causal pathogen of acute endocarditis, a rapidly progressing, destructive infection of the heart valves. Bacterial colonization occurs at sites of endothelial damage, where (together with fibrin and platelets) it initiates the formati...

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Detalles Bibliográficos
Autores principales: Panizzi, Peter, Nahrendorf, Matthias, Figueiredo, Jose-Luiz, Panizzi, Jennifer, Marinelli, Brett, Iwamoto, Yoshi, Keliher, Edmund, Maddur, Ashoka A., Waterman, Peter, Kroh, Heather K., Leuschner, Florian, Aikawa, Elena, Swirski, Filip K., Pittet, Mikael J., Hackeng, Tilman M., Fuentes-Prior, Pablo, Schneewind, Olaf, Bock, Paul E., Weissleder, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169740/
https://www.ncbi.nlm.nih.gov/pubmed/21857652
http://dx.doi.org/10.1038/nm.2423

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