Risk alleles for chronic hepatitis B are associated with decreased mRNA expression of HLA-DPA1 and HLA-DPB1 in normal human liver

A genome-wide association study identified single nucleotide polymorphisms (SNPs) rs3077 and rs9277535 located in the 3′ untranslated regions of human leukocyte antigen (HLA) class II genes HLA-DPA1 and HLA-DPB1, respectively, as the independent variants most strongly associated with chronic hepatit...

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Detalles Bibliográficos
Autores principales: O'Brien, T R, Kohaar, I, Pfeiffer, R M, Maeder, D, Yeager, M, Schadt, E E, Prokunina-Olsson, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169805/
https://www.ncbi.nlm.nih.gov/pubmed/21346778
http://dx.doi.org/10.1038/gene.2011.11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169805/
https://www.ncbi.nlm.nih.gov/pubmed/21346778
http://dx.doi.org/10.1038/gene.2011.11

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